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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2070
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Agtr1a
Name: angiotensin II receptor, type 1a
Acc ID: CHEBI:17234
Term: glucose
Definition: An aldohexose used as a source of energy and metabolic intermediate.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Agtr1aincreases expressionISOAGTR1 (Homo sapiens)6480464CTDGlucose results in increased expression of AGTR1 mRNA; Glucose results in increased expression of AGTR1 proteinPMID:16452552 PMID:31655124 PMID:34464088
Agtr1aincreases expressionISOAgtr1a (Mus musculus)6480464CTDGlucose results in increased expression of AGTR1 proteinPMID:29266779
Agtr1amultiple interactionsISOAGTR1 (Homo sapiens)6480464CTDEnalaprilat inhibits the reaction [Glucose results in increased expression of AGTR1 protein]PMID:16452552
Agtr1amultiple interactionsISOAgtr1a (Mus musculus)6480464CTDCEBPB protein inhibits the reaction [Glucose results in increased expression of AGTR1 protein]PMID:29266779
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