GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Sirt3 | decreases expression | ISO | SIRT3 (Homo sapiens) | 6480464 | CTD | Glucose results in decreased expression of SIRT3 protein | PMID:37417536 | Sirt3 | increases expression | ISO | SIRT3 (Homo sapiens) | 6480464 | CTD | Glucose deficiency results in increased expression of SIRT3 protein | PMID:23494737 | Sirt3 | multiple interactions | ISO | SIRT3 (Homo sapiens) | 6480464 | CTD | polyethylene glycol loxenatide inhibits the reaction [Glucose results in decreased expression of SIRT3 protein]; SIRT3 protein inhibits the reaction [Glucose results in increased acetylation of FOXO1 protein]; SIRT3 protein inhibits the reaction [Glucose results in increased expression of CAT protein]; SIRT3 protein inhibits the reaction [Glucose results in increased expression of CDKN2A protein alternative form]; SIRT3 protein inhibits the reaction [Glucose results in increased expression of GLB1 protein]; SIRT3 protein inhibits the reaction [Glucose results in increased expression of SOD2 protein] | PMID:23494737 PMID:37417536 | Sirt3 | multiple interactions | ISO | Sirt3 (Mus musculus) | 6480464 | CTD | SIRT3 protein inhibits the reaction [sodium arsenite inhibits the reaction [INS1 protein results in increased uptake of Glucose]] | PMID:25979314 | |
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