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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2456
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp17a1
Name: cytochrome P450, family 17, subfamily a, polypeptide 1
Acc ID: CHEBI:1712
Term: 3alpha-hydroxy-5beta-pregnan-20-one
Definition: The 3alpha-stereoisomer of 3-hydroxy-5beta-pregnan-20-one.
Chemical ID: MESH:D011280
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp17a1increases hydroxylationISOCYP17A1 (Homo sapiens)6480464CTDCYP17A1 protein results in increased hydroxylation of Pregnanolone analogPMID:14522586
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