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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3640
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Scnn1b
Name: sodium channel epithelial 1 subunit beta
Acc ID: CHEBI:17026
Term: progesterone
Definition: A C21-steroid hormone in which a pregnane skeleton carries oxo substituents at positions 3 and 20 and is unsaturated at C(4)-C(5). As a hormone, it is involved in the female menstrual cycle, pregnancy and embryogenesis of humans and other species.
Chemical ID: MESH:D011374
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Scnn1baffects expressionEXP 6480464CTDProgesterone affects the expression of SCNN1B mRNA; Progesterone affects the expression of SCNN1B proteinPMID:17939260
Scnn1bmultiple interactionsEXP 6480464CTDProgesterone affects the activity of [SCNN1A protein binds to SCNN1B protein binds to SCNN1G protein]; Progesterone results in decreased activity of [SCNN1A protein binds to SCNN1B protein binds to SCNN1G protein]PMID:16172119 PMID:17939260
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