GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Esr2 | decreases expression | EXP | | 6480464 | CTD | Progesterone results in decreased expression of ESR2 mRNA | PMID:19094096 | Esr2 | multiple interactions | EXP | | 6480464 | CTD | [Estradiol co-treated with Progesterone] results in decreased expression of ESR2 mRNA; Progesterone inhibits the reaction [Estradiol results in increased expression of ESR2 mRNA] | PMID:19094096 PMID:21277368 | Esr2 | affects binding | ISO | ESR2 (Homo sapiens) | 6480464 | CTD | Progesterone binds to ESR2 protein | PMID:19913605 | Esr2 | increases expression | ISO | ESR2 (Homo sapiens) | 6480464 | CTD | Progesterone metabolite results in increased expression of ESR2 mRNA | PMID:17683929 | Esr2 | multiple interactions | ISO | Esr2 (Mus musculus) | 6480464 | CTD | ESR2 affects the reaction [[Estradiol co-treated with Progesterone] results in increased expression of OXT mRNA]; Progesterone inhibits the reaction [ESR2 protein promotes the reaction [Estradiol results in increased expression of LPL mRNA]] | PMID:12834440 PMID:17974624 | |
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