GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Slc7a11 | increases expression | ISO | SLC7A11 (Homo sapiens) | 6480464 | CTD | Bilirubin results in increased expression of SLC7A11 mRNA | PMID:22216172 | Slc7a11 | multiple interactions | ISO | SLC7A11 (Homo sapiens) | 6480464 | CTD | [[[Bilirubin results in increased activity of [SLC7A11 protein co-treated with SLC3A2 protein]] which results in increased uptake of Cystine] which results in increased abundance of Glutathione] which results in decreased susceptibility to Hydrogen Peroxide; [[Bilirubin results in increased activity of [SLC7A11 protein co-treated with SLC3A2 protein]] which results in increased uptake of Cystine] which results in increased abundance of Glutathione; [Bilirubin results in increased activity of [SLC7A11 protein co-treated with SLC3A2 protein]] which results in increased uptake of Cystine; Bilirubin results in increased activity of [SLC7A11 protein co-treated with SLC3A2 protein] | PMID:22216172 | | ||||||||||||||||||||||
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