GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ednra | affects response to substance | EXP | | 6480464 | CTD | EDNRA protein affects the susceptibility to Desoxycorticosterone | PMID:12600921 | Ednra | multiple interactions | EXP | | 6480464 | CTD | [5-(dimethylamino)-N-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide binds to and results in decreased activity of EDNRA protein] inhibits the reaction [Desoxycorticosterone results in increased chemical synthesis of Reactive Oxygen Species]; [Desoxycorticosterone co-treated with Sodium Chloride] results in increased expression of EDNRA protein | PMID:16271043 PMID:22431579 | |
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