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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2891
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il1b
Name: interleukin 1 beta
Acc ID: CHEBI:16962
Term: cortisone
Definition: A C21-steroid that is pregn-4-ene substituted by hydroxy groups at positions 17 and 21 and oxo group at positions 3, 11 and 20.
Chemical ID: MESH:D003348
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il1bdecreases expressionISOIL1B (Homo sapiens)6480464CTDCortisone results in decreased expression of IL1BPMID:27288094
Il1bmultiple interactionsISOIL1B (Homo sapiens)6480464CTDperfluorooctane sulfonic acid inhibits the reaction [Cortisone results in decreased expression of IL1B]PMID:27288094
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