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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68384
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ccnd1
Name: cyclin D1
Acc ID: CHEBI:16907
Term: 4-nitroquinoline N-oxide
Definition: A quinoline N-oxide carrying a nitro substituent at position 4.
Chemical ID: MESH:D015112
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ccnd1increases expressionISOCcnd1 (Mus musculus)6480464CTD4-Nitroquinoline-1-oxide results in increased expression of CCND1 mRNAPMID:27148699
Ccnd1multiple interactionsISOCCND1 (Homo sapiens)6480464CTD[4-Nitroquinoline-1-oxide co-treated with HRAS] results in increased expression of CCND1 mRNA; nimesulide inhibits the reaction [[4-Nitroquinoline-1-oxide co-treated with HRAS] results in increased expression of CCND1 mRNA]PMID:20043093
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