GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tp53 | decreases abundance | ISO | TP53 (Homo sapiens) | 6480464 | CTD | TP53 protein results in decreased abundance of Glutathione | PMID:12967322 | Tp53 | increases expression | ISO | TP53 (Homo sapiens) | 6480464 | CTD | Glutathione results in increased expression of TP53 protein | PMID:10897038 | Tp53 | increases glutathionylation | ISO | TP53 (Homo sapiens) | 6480464 | CTD | Glutathione results in increased glutathionylation of TP53 protein | PMID:17555331 | Tp53 | multiple interactions | ISO | TP53 (Homo sapiens) | 6480464 | CTD | [Buthionine Sulfoximine results in decreased abundance of Glutathione] inhibits the reaction [Benzo(a)pyrene results in increased activity of TP53 protein]; Dithiothreitol inhibits the reaction [Glutathione results in increased glutathionylation of TP53 protein]; Glutathione inhibits the reaction [[CD40LG protein co-treated with IL4 protein] results in increased expression of TP53 protein]; Glutathione inhibits the reaction [diallyl disulfide results in increased expression of TP53 protein]; Glutathione inhibits the reaction [Doxorubicin results in increased expression of TP53 protein] | PMID:12807757 PMID:17555331 PMID:19202565 PMID:22927544 PMID:27634759 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |