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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2886
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il10
Name: interleukin 10
Acc ID: CHEBI:16842
Term: formaldehyde
Definition: An aldehyde resulting from the formal oxidation of methanol.
Chemical ID: MESH:D005557
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il10decreases expressionEXP 6480464CTDFormaldehyde results in decreased expression of IL10 mRNAPMID:24844129
Il10multiple interactionsEXP 6480464CTDAscorbic Acid inhibits the reaction [Formaldehyde promotes the reaction [Lipopolysaccharides results in increased expression of IL10 mRNA]]; Formaldehyde promotes the reaction [Lipopolysaccharides results in increased expression of IL10 mRNA]; Formaldehyde promotes the reaction [Lipopolysaccharides results in increased expression of IL10 protein]PMID:25845602 PMID:27020608
Il10affects expressionISOIl10 (Mus musculus)6480464CTDFormaldehyde affects the expression of IL10 proteinPMID:19422874
Il10decreases expressionISOIL10 (Homo sapiens)6480464CTDFormaldehyde results in decreased expression of IL10 mRNA; Formaldehyde results in decreased expression of IL10 proteinPMID:18849615
Il10multiple interactionsISOIl10 (Mus musculus)6480464CTDFormaldehyde promotes the reaction [ovalbumin-alum results in increased secretion of IL10 protein]PMID:37105513
Il10multiple interactionsISOIL10 (Homo sapiens)6480464CTDFormaldehyde results in increased expression of and results in increased secretion of IL10 proteinPMID:18082304
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