GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Pparg | decreases expression | ISO | PPARG (Homo sapiens) | 6480464 | CTD | Melatonin results in decreased expression of PPARG mRNA | PMID:20738756 | Pparg | increases expression | ISO | PPARG (Homo sapiens) | 6480464 | CTD | Melatonin results in increased expression of PPARG mRNA; Melatonin results in increased expression of PPARG protein | PMID:29734669 PMID:33962019 | Pparg | multiple interactions | ISO | PPARG (Homo sapiens) | 6480464 | CTD | GW 1929 inhibits the reaction [Melatonin results in increased expression of PPARG protein]; luzindole inhibits the reaction [Melatonin results in increased expression of PPARG protein]; Melatonin promotes the reaction [Pioglitazone results in increased expression of PPARG protein]; Pioglitazone promotes the reaction [Melatonin results in increased expression of PPARG protein] | PMID:29734669 | |
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