GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Abcc2 | affects expression | EXP | | 6480464 | CTD | Chenodeoxycholic Acid affects the expression of ABCC2 mRNA | PMID:20888898 | Abcc2 | multiple interactions | EXP | | 6480464 | CTD | ABCC2 protein affects the reaction [verlukast results in decreased secretion of Chenodeoxycholic Acid]; Chenodeoxycholic Acid inhibits the reaction [Ethinyl Estradiol results in decreased expression of ABCC2 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Chenodeoxycholic Acid inhibits the reaction [Ethinyl Estradiol results in decreased expression of ABCC2 mRNA]] | PMID:21262925 PMID:27743861 | Abcc2 | increases expression | ISO | Abcc2 (Mus musculus) | 6480464 | CTD | Chenodeoxycholic Acid results in increased expression of ABCC2 mRNA | PMID:25582706 | Abcc2 | increases expression | ISO | ABCC2 (Homo sapiens) | 6480464 | CTD | Chenodeoxycholic Acid results in increased expression of ABCC2 mRNA | PMID:25055961 | Abcc2 | multiple interactions | ISO | Abcc2 (Mus musculus) | 6480464 | CTD | Chenodeoxycholic Acid promotes the reaction [Carbon Tetrachloride results in increased expression of ABCC2 mRNA] | PMID:25747392 | Abcc2 | multiple interactions | ISO | ABCC2 (Homo sapiens) | 6480464 | CTD | [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in increased expression of ABCC2 mRNA; [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in decreased expression of ABCC2 mRNA; [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of ABCC2 mRNA | PMID:33819548 | | ||||||||||||||||||||||
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