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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1565748 Species: Rattus norvegicus RGD Object: Gene Symbol: Slc51b Name: solute carrier family 51, beta subunit

Acc ID: CHEBI:16755 Term: chenodeoxycholic acid Definition: A dihydroxy-5beta-cholanic acid that has formula C24H40O4. CasRN: 474-25-9 Chemical ID: MESH:D002635

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases expression	ISO	RGD:1604245	6480464	CTD	Chenodeoxycholic Acid results in increased expression of OSTBETA mRNA Chenodeoxycholic Acid results in increased expression of OSTBETA protein Chenodeoxycholic Acid results in increased expression of SLC51B protein Chenodeoxycholic Acid results in increased expression of SLC51B mRNA	PMID:16423920
multiple interactions	ISO	RGD:1604245	6480464	CTD	NR1H4 protein affects the reaction [Chenodeoxycholic Acid results in increased expression of OSTBETA mRNA] NR1H4 protein affects the reaction [Chenodeoxycholic Acid results in increased expression of SLC51B mRNA]	PMID:16423920
multiple interactions	ISO	RGD:1604245	6480464	CTD	epigallocatechin gallate inhibits the reaction [Chenodeoxycholic Acid results in increased expression of SLC51B mRNA]	PMID:22178739
increases expression	ISO	RGD:1604245	6480464	CTD	Chenodeoxycholic Acid results in increased expression of SLC51B mRNA	PMID:16423920 PMID:22178739