GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mdm2 | multiple interactions | EXP | | 6480464 | CTD | [Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in increased expression of MDM2 mRNA | PMID:17905399 | Mdm2 | increases expression | ISO | Mdm2 (Mus musculus) | 6480464 | CTD | Benzene results in increased expression of MDM2 mRNA | PMID:11896287 PMID:15342939 PMID:15935812 | Mdm2 | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | CTD | MDM2 gene polymorphism affects the reaction [CDKN2A gene polymorphism affects the susceptibility to Benzene] | PMID:19596022 | Mdm2 | multiple interactions | ISO | Mdm2 (Mus musculus) | 6480464 | CTD | TRP53 protein affects the reaction [Benzene results in increased expression of MDM2 mRNA] | PMID:11896287 | |
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