GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Psen1 | decreases methylation | ISO | Psen1 (Mus musculus) | 6480464 | CTD | S-Adenosylhomocysteine results in decreased methylation of PSEN1 promoter | PMID:19635394 | Psen1 | increases expression | ISO | Psen1 (Mus musculus) | 6480464 | CTD | S-Adenosylhomocysteine results in increased expression of PSEN1 protein | PMID:19635394 | Psen1 | multiple interactions | ISO | Psen1 (Mus musculus) | 6480464 | CTD | Betaine inhibits the reaction [S-Adenosylhomocysteine results in decreased methylation of PSEN1 promoter] | PMID:19635394 | |
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