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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69218 Species: Mus musculus RGD Object: Gene Symbol: Aldh2 Name: aldehyde dehydrogenase 2, mitochondrial

Acc ID: CHEBI:16643 Term: L-methionine Definition: The L-enantiomer of methionine. CasRN: 63-68-3 Chemical ID: MESH:D008715

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	EXP		6480464	CTD	[Betaine co-treated with Choline co-treated with Folic Acid co-treated with Methionine co-treated with Vitamin B 12 co-treated with Zinc Sulfate co-treated with Ethanol] results in increased expression of ALDH2 protein	PMID:20118189
multiple interactions	EXP		6480464	CTD	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of ALDH2 mRNA	PMID:20938992