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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2926
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Itgam
Name: integrin subunit alpha M
Acc ID: CHEBI:16643
Term: L-methionine
Definition: The L-enantiomer of methionine.
Chemical ID: MESH:D008715
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Itgammultiple interactionsISOItgam (Mus musculus)6480464CTD[Choline deficiency co-treated with Methionine deficiency] results in increased expression of ITGAM mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Dietary Fats] results in increased expression of ITGAM mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ITGAM mRNA; Choline inhibits the reaction [[Choline deficiency co-treated with Methionine deficiency] results in increased expression of ITGAM mRNA]; Methionine inhibits the reaction [[Choline deficiency co-treated with Methionine deficiency] results in increased expression of ITGAM mRNA]; Smoke affects the reaction [[Methionine deficiency co-treated with Choline deficiency co-treated with Dietary Fats] results in increased expression of ITGAM mRNA]PMID:20938992 PMID:25178843 PMID:31678261
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