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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3227
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Odc1
Name: ornithine decarboxylase 1
Acc ID: CHEBI:16610
Term: spermidine
Definition: A triamine that is the 1,5,10-triaza derivative of decane.
Chemical ID: MESH:D013095
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Odc1multiple interactionsEXP 6480464CTD[[Ornithine Decarboxylase Inhibitors results in decreased activity of ODC1 protein] which results in decreased chemical synthesis of Polyamines] which results in decreased abundance of Spermidine; [ODC1 protein results in increased chemical synthesis of Polyamines] which results in increased abundance of Spermidine; [Pentanoic Acids results in decreased activity of ODC1 protein] which results in decreased abundance of SpermidinePMID:20805360 PMID:22555848
Odc1increases abundanceISOOdc1 (Mus musculus)6480464CTDODC1 protein results in increased abundance of SpermidinePMID:22555848
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