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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68353
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nr5a2
Name: nuclear receptor subfamily 5, group A, member 2
Acc ID: CHEBI:16602
Term: trichloroethene
Definition: A member of the class of chloroethenes that is ethene substituted by chloro groups at positions 1, 1 and 2.
Chemical ID: MESH:D014241
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nr5a2increases expressionEXP 6480464CTDTrichloroethylene results in increased expression of NR5A2 mRNAPMID:33387578
Nr5a2multiple interactionsISONr5a2 (Mus musculus)6480464CTDPPARA protein inhibits the reaction [Trichloroethylene results in decreased expression of NR5A2 mRNA]PMID:15363585
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