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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620537
Species: Rattus norvegicus
RGD Object: Gene
Symbol: C3ar1
Name: complement C3a receptor 1
Acc ID: CHEBI:16602
Term: trichloroethene
Definition: A member of the class of chloroethenes that is ethene substituted by chloro groups at positions 1, 1 and 2.
Chemical ID: MESH:D014241
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
C3ar1increases expressionEXP 6480464CTDTrichloroethylene results in increased expression of C3AR1 mRNAPMID:33387578
C3ar1increases expressionISOC3ar1 (Mus musculus)6480464CTDTrichloroethylene results in increased expression of C3AR1 proteinPMID:24974766
C3ar1multiple interactionsISOC3ar1 (Mus musculus)6480464CTDSB 290157 inhibits the reaction [Trichloroethylene results in increased expression of C3AR1 protein]PMID:24974766
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