GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ccnd3 | decreases expression | EXP | | 6480464 | CTD | Trichloroethylene results in decreased expression of CCND3 mRNA | PMID:33387578 | Ccnd3 | increases expression | ISO | Ccnd3 (Mus musculus) | 6480464 | CTD | Trichloroethylene results in increased expression of CCND3 mRNA | PMID:15363585 | Ccnd3 | multiple interactions | ISO | Ccnd3 (Mus musculus) | 6480464 | CTD | [[ALB protein binds to 4-hydroxy-2-nonenal] which results in increased susceptibility to Trichloroethylene] which results in increased expression of CCND3 protein; PPARA protein inhibits the reaction [Trichloroethylene results in increased expression of CCND3 protein]; sulforaphane inhibits the reaction [[[ALB protein binds to 4-hydroxy-2-nonenal] which results in increased susceptibility to Trichloroethylene] which results in increased expression of CCND3 protein] | PMID:15363585 PMID:33007382 | | ||||||||||||||||||||||
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