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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2004
Species: Rattus norvegicus
RGD Object: Gene
Symbol: A2m
Name: alpha-2-macroglobulin
Acc ID: CHEBI:16586
Term: 6-aminohexanoic acid
Definition: An epsilon-amino acid comprising hexanoic acid carrying an amino substituent at position C-6. Used to control postoperative bleeding, and to treat overdose effects of the thrombolytic agents streptokinase and tissue plasminogen activator.
Chemical ID: MESH:D015119
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
A2mdecreases expressionISOA2M (Homo sapiens)6480464CTDAminocaproic Acid results in decreased expression of A2M proteinPMID:11304663
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