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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61817 Species: Rattus norvegicus RGD Object: Gene Symbol: Col1a1 Name: collagen, type I, alpha 1

Acc ID: CHEBI:16494 Term: lipoic acid Definition: A heterocyclic thia fatty acid comprising pentanoic acid with a 1,2-dithiolan-3-yl group at the 5-position. CasRN: 62-46-4 Chemical ID: MESH:D008063

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	EXP		6480464	CTD	Thioctic Acid inhibits the reaction [Thioacetamide results in increased expression of COL1A1 mRNA]	PMID:21251946