GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nos1 | decreases expression | EXP | | 6480464 | CTD | Nitric Oxide deficiency results in decreased expression of NOS1 protein | PMID:15249212 PMID:24184442 | Nos1 | increases chemical synthesis | EXP | | 6480464 | CTD | NOS1 protein results in increased chemical synthesis of Nitric Oxide | PMID:17098364 | Nos1 | multiple interactions | EXP | | 6480464 | CTD | [Calcium binds to CALM1 protein] promotes the reaction [NOS1 protein results in increased chemical synthesis of Nitric Oxide]; [Cisplatin results in increased expression of NOS1 mRNA] which results in increased abundance of Nitric Oxide; [EDN1 protein results in increased activity of NOS1 protein] which results in increased abundance of Nitric Oxide; [Formaldehyde results in increased expression of NOS1 protein] which results in increased abundance of Nitric Oxide; [NOS1 protein results in increased reduction of Trinitrotoluene] which results in decreased chemical synthesis of Nitric Oxide | PMID:15223068 PMID:16380457 PMID:17098364 PMID:19038279 PMID:23359814 | Nos1 | increases chemical synthesis | ISO | NOS1 (Homo sapiens) | 6480464 | CTD | NOS1 protein results in increased chemical synthesis of Nitric Oxide | PMID:25766886 | Nos1 | multiple interactions | ISO | Nos1 (Mus musculus) | 6480464 | CTD | 7-nitroindazole inhibits the reaction [[N-isopropylbenzylamine results in increased expression of NOS1 protein] which results in increased abundance of Nitric Oxide]; [N-isopropylbenzylamine results in increased expression of NOS1 protein] which results in increased abundance of Nitric Oxide; PLAT protein affects the reaction [NOS1 protein results in increased chemical synthesis of Nitric Oxide] | PMID:18195371 PMID:36162621 | | ||||||||||||||||||||||
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