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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 631379
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp26b1
Name: cytochrome P450, family 26, subfamily b, polypeptide 1
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp26b1decreases expressionISOCYP26B1 (Homo sapiens)6480464CTDEstradiol results in decreased expression of CYP26B1 mRNAPMID:19619570 PMID:32088792
Cyp26b1increases expressionISOCYP26B1 (Homo sapiens)6480464CTDEstradiol results in increased expression of CYP26B1 mRNAPMID:31614463
Cyp26b1multiple interactionsISOCYP26B1 (Homo sapiens)6480464CTD[Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of CYP26B1 mRNA; [Estradiol co-treated with TGFB1 protein] results in increased expression of CYP26B1 mRNAPMID:19619570 PMID:30165855
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