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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621870
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ugcg
Name: UDP-glucose ceramide glucosyltransferase
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ugcgincreases expressionISOUGCG (Homo sapiens)6480464CTDEstradiol results in increased expression of UGCG mRNAPMID:19619570 PMID:31614463
Ugcgmultiple interactionsISOUGCG (Homo sapiens)6480464CTD[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of UGCG mRNA; [Estradiol co-treated with Progesterone] results in decreased expression of UGCG mRNA; [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of UGCG mRNAPMID:19619570 PMID:20660070 PMID:20823114
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