GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Erbb4 | decreases expression | ISO | ERBB4 (Homo sapiens) | 6480464 | CTD | Estradiol results in decreased expression of ERBB4 mRNA | PMID:17872378 PMID:19619570 PMID:21185374 | Erbb4 | multiple interactions | ISO | ERBB4 (Homo sapiens) | 6480464 | CTD | [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of ERBB4 mRNA; ERBB4 protein promotes the reaction [Estradiol results in increased expression of PGR mRNA]; Raloxifene Hydrochloride inhibits the reaction [Estradiol results in decreased expression of ERBB4 mRNA] | PMID:19619570 PMID:20550710 PMID:21185374 | |
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