GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Sox9 | affects expression | ISO | SOX9 (Homo sapiens) | 6480464 | CTD | Estradiol affects the expression of SOX9 mRNA | PMID:14699072 | Sox9 | decreases expression | ISO | SOX9 (Homo sapiens) | 6480464 | CTD | Estradiol results in decreased expression of SOX9 mRNA | PMID:19167446 PMID:20106945 | Sox9 | decreases expression | ISO | Sox9 (Mus musculus) | 6480464 | CTD | Estradiol results in decreased expression of SOX9 mRNA | PMID:19484750 | Sox9 | increases expression | ISO | SOX9 (Homo sapiens) | 6480464 | CTD | Estradiol results in increased expression of SOX9 mRNA | PMID:19619570 | Sox9 | increases expression | ISO | Sox9 (Mus musculus) | 6480464 | CTD | Estradiol results in increased expression of SOX9 mRNA | PMID:25210133 | Sox9 | multiple interactions | ISO | SOX9 (Homo sapiens) | 6480464 | CTD | [Arsenic co-treated with Estradiol] results in decreased expression of SOX9 mRNA; [Estradiol co-treated with EGF protein] results in increased expression of SOX9 mRNA; [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of SOX9 mRNA; [Estradiol co-treated with TGFB1 protein] results in increased expression of SOX9 mRNA; [Progesterone co-treated with Estradiol] results in decreased expression of SOX9 mRNA | PMID:17404688 PMID:19619570 PMID:24758408 PMID:30165855 PMID:33047385 | Sox9 | multiple interactions | ISO | Sox9 (Mus musculus) | 6480464 | CTD | ESR1 protein promotes the reaction [Estradiol results in increased expression of SOX9 mRNA] | PMID:25210133 | |
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