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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620017
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tgfbi
Name: transforming growth factor, beta induced
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tgfbiincreases expressionEXP 6480464CTDEstradiol results in increased expression of TGFBI mRNAPMID:32145629
Tgfbimultiple interactionsEXP 6480464CTD[estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of TGFBI mRNAPMID:32741896
Tgfbidecreases expressionISOTgfbi (Mus musculus)6480464CTDEstradiol results in decreased expression of TGFBI mRNAPMID:15289156
Tgfbiincreases expressionISOTGFBI (Homo sapiens)6480464CTDEstradiol results in increased expression of TGFBI mRNAPMID:19619570
Tgfbimultiple interactionsISOTGFBI (Homo sapiens)6480464CTD[Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of TGFBI mRNA; [Estradiol co-treated with TGFB1 protein] results in increased expression of TGFBI mRNAPMID:19619570 PMID:30165855
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