GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Prkca | multiple interactions | EXP | | 6480464 | CTD | [bisphenol A co-treated with Estradiol] results in decreased expression of PRKCA mRNA | PMID:26496021 | Prkca | decreases activity | ISO | PRKCA (Homo sapiens) | 6480464 | CTD | Estradiol results in decreased activity of PRKCA protein | PMID:8946564 | Prkca | increases expression | ISO | PRKCA (Homo sapiens) | 6480464 | CTD | Estradiol results in increased expression of PRKCA mRNA | PMID:19619570 | Prkca | increases phosphorylation | ISO | PRKCA (Homo sapiens) | 6480464 | CTD | Estradiol results in increased phosphorylation of PRKCA protein | PMID:23000059 | Prkca | multiple interactions | ISO | PRKCA (Homo sapiens) | 6480464 | CTD | [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of PRKCA mRNA; RICTOR mutant form inhibits the reaction [Estradiol results in increased phosphorylation of PRKCA protein]; Sirolimus inhibits the reaction [Estradiol results in increased phosphorylation of PRKCA protein] | PMID:19619570 PMID:23000059 | |
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