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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3239
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Oxtr
Name: oxytocin receptor
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Oxtrincreases expressionEXP 6480464CTDEstradiol results in increased expression of OXTR mRNA; Estradiol results in increased expression of OXTR proteinPMID:23664861
Oxtrdecreases expressionISOOXTR (Homo sapiens)6480464CTDEstradiol results in decreased expression of OXTR mRNAPMID:19167446 PMID:24758408
Oxtrincreases expressionISOOxtr (Mus musculus)6480464CTDEstradiol results in increased expression of OXTR mRNAPMID:19484750 PMID:30077407
Oxtrincreases expressionISOOXTR (Homo sapiens)6480464CTDEstradiol results in increased expression of OXTR mRNAPMID:31614463
Oxtrmultiple interactionsISOOxtr (Mus musculus)6480464CTD[Polyphenols co-treated with Estradiol] results in increased expression of OXTR mRNAPMID:30077407
Oxtrmultiple interactionsISOOXTR (Homo sapiens)6480464CTDEGF protein inhibits the reaction [Estradiol results in decreased expression of OXTR mRNA]PMID:24758408
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