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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3054
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mbp
Name: myelin basic protein
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mbpdecreases expressionISOMbp (Mus musculus)6480464CTDEstradiol results in decreased expression of MBP mRNAPMID:19484750
Mbpmultiple interactionsISOMbp (Mus musculus)6480464CTD[Progesterone co-treated with Estradiol] inhibits the reaction [Cuprizone results in decreased expression of MBP mRNA]PMID:19031445
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