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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2862
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Idh1
Name: isocitrate dehydrogenase (NADP(+)) 1
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Idh1decreases expressionEXP 6480464CTDEstradiol results in decreased expression of IDH1 proteinPMID:32145629
Idh1multiple interactionsEXP 6480464CTD[bisphenol A co-treated with Estradiol] results in decreased expression of IDH1 mRNAPMID:26496021
Idh1decreases expressionISOIDH1 (Homo sapiens)6480464CTDEstradiol results in decreased expression of IDH1 mRNAPMID:31614463
Idh1multiple interactionsISOIDH1 (Homo sapiens)6480464CTD[Estradiol co-treated with Progesterone] results in increased expression of IDH1 mRNAPMID:20660070
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