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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2366
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcc2
Name: ATP binding cassette subfamily C member 2
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcc2affects transportEXP 6480464CTDABCC2 protein affects the transport of EstradiolPMID:15507541
Abcc2decreases expressionEXP 6480464CTDEstradiol results in decreased expression of ABCC2 mRNAPMID:32145629
Abcc2multiple interactionsEXP 6480464CTDEstradiol affects the localization of and affects the activity of ABCC2 proteinPMID:15374814
Abcc2decreases expressionISOAbcc2 (Mus musculus)6480464CTDEstradiol results in decreased expression of ABCC2 mRNA; Estradiol results in decreased expression of ABCC2 proteinPMID:35802278
Abcc2increases expressionISOABCC2 (Homo sapiens)6480464CTDEstradiol results in increased expression of ABCC2 mRNA; Estradiol results in increased expression of ABCC2 proteinPMID:19580841
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