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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2327
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cebpb
Name: CCAAT/enhancer binding protein beta
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cebpbincreases expressionEXP 6480464CTDEstradiol results in increased expression of CEBPB mRNAPMID:32145629
Cebpbaffects expressionISOCebpb (Mus musculus)6480464CTDEstradiol affects the expression of CEBPB mRNAPMID:15598610
Cebpbdecreases expressionISOCebpb (Mus musculus)6480464CTDEstradiol results in decreased expression of CEBPB mRNAPMID:19484750
Cebpbincreases expressionISOCebpb (Mus musculus)6480464CTDEstradiol results in increased expression of CEBPB mRNAPMID:15289156 PMID:18359623 PMID:25210133
Cebpbincreases expressionISOCEBPB (Homo sapiens)6480464CTDEstradiol results in increased expression of CEBPB mRNAPMID:23373633
Cebpbmultiple interactionsISOCEBPB (Homo sapiens)6480464CTD[Estradiol co-treated with Norethindrone Acetate] results in increased expression of CEBPB mRNA; CEBPB protein affects the reaction [Estradiol results in increased expression of KLRC3 mRNA]; Estradiol promotes the reaction [ESR1 protein binds to CEBPB protein]PMID:17395694 PMID:22217510
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