GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Aqp1 | decreases expression | EXP | | 6480464 | CTD | Estradiol results in decreased expression of AQP1 mRNA | PMID:20381596 PMID:28341573 | Aqp1 | increases expression | EXP | | 6480464 | CTD | Estradiol results in increased expression of AQP1 mRNA; Estradiol results in increased expression of AQP1 protein | PMID:28341573 PMID:32145629 | Aqp1 | multiple interactions | EXP | | 6480464 | CTD | [Estradiol co-treated with Progesterone] results in decreased expression of AQP1 mRNA; [Estradiol co-treated with Progesterone] results in increased expression of AQP1 protein; Quercetin inhibits the reaction [[Estradiol co-treated with Progesterone] results in decreased expression of AQP1 mRNA]; Quercetin inhibits the reaction [Estradiol results in increased expression of AQP1 protein]; Quercetin promotes the reaction [[Estradiol co-treated with Progesterone] results in increased expression of AQP1 protein]; Quercetin promotes the reaction [Estradiol results in decreased expression of AQP1 mRNA] | PMID:28341573 | Aqp1 | decreases expression | ISO | Aqp1 (Mus musculus) | 6480464 | CTD | Estradiol results in decreased expression of AQP1 mRNA | PMID:26879975 | | ||||||||||||||||||||||
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