Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2070
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Agtr1a
Name: angiotensin II receptor, type 1a
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Agtr1aincreases expressionEXP 6480464CTDEstradiol results in increased expression of AGTR1 mRNA; Estradiol results in increased expression of AGTR1A mRNAPMID:17021606 PMID:32145629
Agtr1adecreases expressionISOAGTR1 (Homo sapiens)6480464CTDEstradiol results in decreased expression of AGTR1 mRNAPMID:15159206 PMID:20106945 PMID:21632981
Agtr1amultiple interactionsISOAGTR1 (Homo sapiens)6480464CTDEstradiol inhibits the reaction [AGT protein results in increased expression of AGTR1 mRNA]; Estradiol inhibits the reaction [AGT protein results in increased expression of AGTR1 protein]PMID:16097371
Go Back to source page   Continue to Ontology report