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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1319009 Species: Homo sapiens RGD Object: Gene Symbol: BNIP2 Name: BCL2/adenovirus E1B 19kDa interacting protein 2

Acc ID: CHEBI:16469 Term: 17beta-estradiol Definition: The 17beta-isomer of estradiol. CasRN: 50-28-2 Chemical ID: MESH:D004958

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
affects expression	EXP		6480464	CTD	Estradiol affects the expression of BNIP2	PMID:11424952
decreases expression	EXP		6480464	CTD	Estradiol results in decreased expression of BNIP2 mRNA	PMID:9169520
decreases expression	ISO	RGD:1308944	6480464	CTD	Estradiol results in decreased expression of BNIP2 mRNA	PMID:10715586