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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1311706
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hdac11
Name: histone deacetylase 11
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hdac11decreases expressionEXP 6480464CTDEstradiol results in decreased expression of HDAC11 mRNAPMID:32145629
Hdac11affects expressionISOHDAC11 (Homo sapiens)6480464CTDEstradiol affects the expression of HDAC11 mRNAPMID:22574217
Hdac11increases expressionISOHDAC11 (Homo sapiens)6480464CTDEstradiol results in increased expression of HDAC11 mRNAPMID:24758408
Hdac11multiple interactionsISOHDAC11 (Homo sapiens)6480464CTDEGF protein inhibits the reaction [Estradiol results in increased expression of HDAC11 mRNA]PMID:24758408
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