GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mapk14 | increases phosphorylation | EXP | | 6480464 | CTD | Lipopolysaccharides results in increased phosphorylation of MAPK14 protein | PMID:31707400 | Mapk14 | multiple interactions | EXP | | 6480464 | CTD | [kaempferol inhibits the reaction [Lipopolysaccharides co-treated with HIF1A protein]] which results in increased expression of MAPK14 protein; [kaempferol inhibits the reaction [Lipopolysaccharides co-treated with TNF protein]] which results in increased phosphorylation of MAPK14 protein; [Lipopolysaccharides co-treated with TNF protein] results in increased phosphorylation of MAPK14 protein; [SB 203580 inhibits the reaction [Lipopolysaccharides co-treated with TNF protein]] which results in increased phosphorylation of MAPK14 protein; alisol B 23-acetate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein] | PMID:31707400 PMID:36049518 | Mapk14 | decreases activity | ISO | MAPK14 (Homo sapiens) | 6480464 | CTD | Lipopolysaccharides results in decreased activity of MAPK14 protein | PMID:14997032 | Mapk14 | increases expression | ISO | Mapk14 (Mus musculus) | 6480464 | CTD | Lipopolysaccharides results in increased expression of MAPK14 mRNA | PMID:25843059 PMID:35833596 | Mapk14 | increases phosphorylation | ISO | MAPK14 (Homo sapiens) | 6480464 | CTD | Lipopolysaccharides results in increased phosphorylation of MAPK14 protein | PMID:21911040 PMID:22124178 PMID:22226621 PMID:26037075 | Mapk14 | increases phosphorylation | ISO | Mapk14 (Mus musculus) | 6480464 | CTD | Lipopolysaccharides results in increased phosphorylation of MAPK14 protein | PMID:10704466 PMID:15778123 PMID:15933225 PMID:16023107 PMID:16899239 PMID:22155221 PMID:22155741 PMID:22180763 PMID:29191728 PMID:31707400 | Mapk14 | multiple interactions | ISO | MAPK14 (Homo sapiens) | 6480464 | CTD | ARHGEF2 mutant form inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]; CEP-11004 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]; DUSP1 mutant form inhibits the reaction [trichostatin A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]]; procyanidin B1 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]; RHOA mutant form inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]; SB 203580 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]; Telmisartan inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]; trichostatin A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]; Y 27632 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein] | PMID:17698565 PMID:21911040 PMID:22124178 PMID:22226621 PMID:26037075 | Mapk14 | multiple interactions | ISO | Mapk14 (Mus musculus) | 6480464 | CTD | 1-dodecylsulfonyl-5N,6O-oxomethylidenenojirimycin promotes the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]; 3,4-dihydroxybenzohydroxamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of MAPK14 mRNA]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in increased expression of MAPK14 mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in increased expression of MAPK14 mRNA]]; alisol B 23-acetate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]; Amifostine inhibits the reaction [Lipopolysaccharides results in increased activity of and results in increased phosphorylation of MAPK14 protein]; Chalcone analog inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]; cordycepin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]; Dexamethasone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAPK14 protein]; Drugs, Chinese Herbal inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAPK14 protein]; DUSP1 protein promotes the reaction [Dexamethasone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAPK14 protein]]; GSTP1 protein inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]; juzentaihoto promotes the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]; Lipopolysaccharides promotes the reaction [Polystyrenes results in increased expression of MAPK14 mRNA]; Lipopolysaccharides results in increased activity of and results in increased phosphorylation of MAPK14 protein; Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAPK14 protein; lycorine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]; MAPK14 protein promotes the reaction [Lipopolysaccharides results in increased expression of TNF protein]; methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]; Polystyrenes promotes the reaction [Lipopolysaccharides results in increased expression of MAPK14 mRNA] | PMID:15778123 PMID:15795323 PMID:15933225 PMID:16023107 PMID:16880258 PMID:16899239 PMID:17996413 PMID:19010997 PMID:22155221 PMID:22155741 PMID:25843059 PMID:29191728 PMID:31707400 PMID:35833596 | | ||||||||||||||||||||||
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