GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nox4 | increases expression | ISO | NOX4 (Homo sapiens) | 6480464 | CTD | Lipopolysaccharides results in increased expression of NOX4 mRNA; Lipopolysaccharides results in increased expression of NOX4 protein | PMID:24835767 | Nox4 | increases expression | ISO | Nox4 (Mus musculus) | 6480464 | CTD | Lipopolysaccharides results in increased expression of NOX4 mRNA; Lipopolysaccharides results in increased expression of NOX4 protein | PMID:24835767 PMID:27568862 | Nox4 | multiple interactions | ISO | NOX4 (Homo sapiens) | 6480464 | CTD | CAV1 mutant form promotes the reaction [Lipopolysaccharides results in increased expression of NOX4 mRNA] | PMID:24835767 | Nox4 | multiple interactions | ISO | Nox4 (Mus musculus) | 6480464 | CTD | [Lipopolysaccharides co-treated with Uric Acid] results in increased expression of NOX4 mRNA; [Lipopolysaccharides co-treated with Uric Acid] results in increased expression of NOX4 protein; Acetylcysteine inhibits the reaction [NOX4 protein promotes the reaction [[Lipopolysaccharides co-treated with IFNG1 protein] results in increased expression of AIF1 protein]]; Acetylcysteine inhibits the reaction [NOX4 protein promotes the reaction [[Lipopolysaccharides co-treated with IFNG1 protein] results in increased expression of CS protein]]; Acetylcysteine inhibits the reaction [NOX4 protein promotes the reaction [[Lipopolysaccharides co-treated with IFNG1 protein] results in increased expression of HK2 protein]]; Acetylcysteine inhibits the reaction [NOX4 protein promotes the reaction [[Lipopolysaccharides co-treated with IFNG1 protein] results in increased expression of IL1B protein]]; Acetylcysteine inhibits the reaction [NOX4 protein promotes the reaction [[Lipopolysaccharides co-treated with IFNG1 protein] results in increased expression of IL6 protein]]; Acetylcysteine inhibits the reaction [NOX4 protein promotes the reaction [[Lipopolysaccharides co-treated with IFNG1 protein] results in increased expression of PKM protein]]; Acetylcysteine inhibits the reaction [NOX4 protein promotes the reaction [[Lipopolysaccharides co-treated with IFNG1 protein] results in increased expression of TNF protein]]; coagulin-L inhibits the reaction [Lipopolysaccharides results in increased expression of NOX4 mRNA]; Dexamethasone inhibits the reaction [Lipopolysaccharides results in increased expression of NOX4 mRNA]; diallyl trisulfide inhibits the reaction [[Lipopolysaccharides co-treated with Uric Acid] results in increased expression of NOX4 mRNA]; diallyl trisulfide inhibits the reaction [[Lipopolysaccharides co-treated with Uric Acid] results in increased expression of NOX4 protein]; NOX4 protein affects the reaction [Lipopolysaccharides results in increased expression of CD86 protein]; NOX4 protein affects the reaction [Lipopolysaccharides results in increased expression of CS protein]; NOX4 protein affects the reaction [Lipopolysaccharides results in increased expression of HK2 protein]; NOX4 protein affects the reaction [Lipopolysaccharides results in increased expression of IL1B protein]; NOX4 protein affects the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; NOX4 protein affects the reaction [Lipopolysaccharides results in increased expression of PKM protein]; NOX4 protein affects the reaction [Lipopolysaccharides results in increased expression of TNF protein]; NOX4 protein promotes the reaction [[Lipopolysaccharides co-treated with IFNG1 protein] results in increased expression of AIF1 protein]; NOX4 protein promotes the reaction [[Lipopolysaccharides co-treated with IFNG1 protein] results in increased expression of CS protein]; NOX4 protein promotes the reaction [[Lipopolysaccharides co-treated with IFNG1 protein] results in increased expression of HK2 protein]; NOX4 protein promotes the reaction [[Lipopolysaccharides co-treated with IFNG1 protein] results in increased expression of IL1B protein]; NOX4 protein promotes the reaction [[Lipopolysaccharides co-treated with IFNG1 protein] results in increased expression of IL6 protein]; NOX4 protein promotes the reaction [[Lipopolysaccharides co-treated with IFNG1 protein] results in increased expression of PKM protein]; NOX4 protein promotes the reaction [[Lipopolysaccharides co-treated with IFNG1 protein] results in increased expression of TNF protein] | PMID:27568862 PMID:36762617 PMID:36796188 | | ||||||||||||||||||||||
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