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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3343
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Plau
Name: plasminogen activator, urokinase
Acc ID: CHEBI:16412
Term: lipopolysaccharide
Definition: Liposaccharide natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria).
Chemical ID: MESH:D008070
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Plauincreases expressionEXP 6480464CTDLipopolysaccharides results in increased expression of PLAU proteinPMID:27098997 PMID:30980805
Plaumultiple interactionsEXP 6480464CTDPlant Extracts inhibits the reaction [Lipopolysaccharides results in increased expression of PLAU protein]; U 0126 inhibits the reaction [Lipopolysaccharides results in increased expression of PLAU protein]PMID:27098997 PMID:30980805
Plauaffects expressionISOPLAU (Homo sapiens)6480464CTDLipopolysaccharides affects the expression of PLAU mRNAPMID:28070326
Plauincreases expressionISOPLAU (Homo sapiens)6480464CTDLipopolysaccharides results in increased expression of PLAU mRNAPMID:18192897
Plaumultiple interactionsISOPLAU (Homo sapiens)6480464CTD[NAT10 protein affects the susceptibility to Lipopolysaccharides] which affects the expression of PLAU mRNA; Plant Extracts affects the reaction [Lipopolysaccharides affects the expression of PLAU mRNA]PMID:28070326 PMID:35877022
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