GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Igf1 | decreases expression | EXP | | 6480464 | CTD | Lipopolysaccharides results in decreased expression of IGF1 protein | PMID:16522730 PMID:31486215 | Igf1 | increases expression | EXP | | 6480464 | CTD | Lipopolysaccharides results in increased expression of IGF1 mRNA; Lipopolysaccharides results in increased expression of IGF1 protein | PMID:16448778 | Igf1 | multiple interactions | EXP | | 6480464 | CTD | [Lipopolysaccharides co-treated with Rutin] results in decreased expression of IGF1 mRNA; gadolinium chloride inhibits the reaction [Lipopolysaccharides results in decreased expression of IGF1 protein]; Honghua extract, Carthamus tinctorius inhibits the reaction [Lipopolysaccharides results in decreased expression of IGF1 protein]; Tretinoin inhibits the reaction [Lipopolysaccharides results in increased expression of IGF1 mRNA]; Tretinoin inhibits the reaction [Lipopolysaccharides results in increased expression of IGF1 protein] | PMID:16448778 PMID:16522730 PMID:28693884 PMID:31486215 | Igf1 | increases expression | ISO | IGF1 (Homo sapiens) | 6480464 | CTD | Lipopolysaccharides results in increased expression of IGF1 mRNA | PMID:35953652 | Igf1 | multiple interactions | ISO | Igf1 (Mus musculus) | 6480464 | CTD | [IGF1 protein co-treated with Lipopolysaccharides] results in decreased expression of TLR4 mRNA; [picropodophyllin co-treated with Lipopolysaccharides] inhibits the reaction [IGF1 protein results in decreased expression of IL1B mRNA]; [picropodophyllin co-treated with Lipopolysaccharides] inhibits the reaction [IGF1 protein results in decreased expression of IL6 mRNA]; [picropodophyllin co-treated with Lipopolysaccharides] inhibits the reaction [IGF1 protein results in decreased expression of TLR4 mRNA]; [picropodophyllin co-treated with Lipopolysaccharides] inhibits the reaction [IGF1 protein results in decreased expression of TNF mRNA]; IGF1 protein inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; IGF1 protein inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; IGF1 protein inhibits the reaction [Lipopolysaccharides results in increased localization of RELA protein] | PMID:21371294 | Igf1 | multiple interactions | ISO | IGF1 (Homo sapiens) | 6480464 | CTD | [nickel chloride co-treated with Lipopolysaccharides] results in increased secretion of IGF1 protein | PMID:18437699 | |
Go Back to source page | Continue to Ontology report |