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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61995
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pten
Name: phosphatase and tensin homolog
Acc ID: CHEBI:16400
Term: gossypetin
Definition: A hexahydroxyflavone having the hydroxy groups placed at the 3-, 3'-, 4'-, 5- 7- and 8-positions.
Chemical ID: MESH:C059922
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ptenincreases expressionISOPTEN (Homo sapiens)6480464CTDgossypetin results in increased expression of PTEN proteinPMID:25622137
Ptenmultiple interactionsISOPTEN (Homo sapiens)6480464CTDEnzyme Inhibitors inhibits the reaction [gossypetin results in increased expression of PTEN protein]PMID:25622137
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