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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621157
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Txn1
Name: thioredoxin 1
Acc ID: CHEBI:16325
Term: lithocholic acid
Definition: A monohydroxy-5beta-cholanic acid with a alpha-hydroxy substituent at position 3. It is a bile acid obtained from chenodeoxycholic acid by bacterial action.
Chemical ID: MESH:D008095
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Txn1increases expressionISOTXN (Homo sapiens)6480464CTDLithocholic Acid results in increased expression of TXN proteinPMID:17724089
Txn1multiple interactionsISOTXN (Homo sapiens)6480464CTD[Lithocholic Acid results in increased activity of NFE2L2 protein] which results in increased expression of TXN mRNAPMID:17724089
Txn1multiple interactionsISOTxn1 (Mus musculus)6480464CTD[Lithocholic Acid results in increased activity of NFE2L2 protein] which results in increased expression of TXN1 mRNAPMID:17724089
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