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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620588
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cd14
Name: CD14 molecule
Acc ID: CHEBI:16325
Term: lithocholic acid
Definition: A monohydroxy-5beta-cholanic acid with a alpha-hydroxy substituent at position 3. It is a bile acid obtained from chenodeoxycholic acid by bacterial action.
Chemical ID: MESH:D008095
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cd14increases expressionISOCD14 (Homo sapiens)6480464CTDLithocholic Acid analog results in increased expression of CD14 mRNA; Lithocholic Acid results in increased expression of CD14 mRNAPMID:18180267 PMID:19244278
Cd14multiple interactionsISOCD14 (Homo sapiens)6480464CTDBenzo(a)pyrene promotes the reaction [Lithocholic Acid results in increased expression of CD14 mRNA]PMID:19244278
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