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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737474 Species: Homo sapiens RGD Object: Gene Symbol: SLC16A1 Name: solute carrier family 16, member 1 (monocarboxylic acid transporter 1)

Acc ID: CHEBI:16243 Term: quercetin Definition: A pentahydroxyflavone having the five hydroxy groups placed at the 3-, 3'-, 4'-, 5- and 7-positions. CasRN: 117-39-5 Chemical ID: MESH:D011794

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	ISO	RGD:3690	6480464	CTD	[Quercetin results in decreased activity of SLC16A1 protein] which results in decreased uptake of Sodium Oxybate	PMID:17108059
multiple interactions	EXP		6480464	CTD	Quercetin inhibits the reaction [SLC16A1 protein results in increased uptake of Benzoic Acid]	PMID:17976262