GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Rela | multiple interactions | EXP | | 6480464 | CTD | Quercetin inhibits the reaction [[IL1B protein co-treated with IFNG protein] affects the localization of and results in increased activity of RELA protein]; Quercetin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] affects the localization of RELA protein]; Quercetin inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of RELA protein]; Quercetin inhibits the reaction [Atrazine results in increased expression of RELA protein]; Quercetin inhibits the reaction [Cyclophosphamide results in increased expression of RELA mRNA]; Quercetin inhibits the reaction [Dehydroepiandrosterone affects the localization of RELA protein]; Quercetin inhibits the reaction [Fructose results in increased phosphorylation of RELA protein]; Quercetin inhibits the reaction [Glucose affects the localization of RELA protein]; Quercetin inhibits the reaction [Glucose results in increased expression of RELA mRNA]; Quercetin inhibits the reaction [Glucose results in increased expression of RELA protein]; Quercetin inhibits the reaction [IL1B protein affects the localization of RELA protein]; Quercetin inhibits the reaction [lead acetate affects the localization of RELA protein] | PMID:18090225 PMID:20542118 PMID:22221676 PMID:22728154 PMID:23070809 PMID:23138875 PMID:23770986 PMID:24491314 PMID:27634381 PMID:34751495 PMID:37419146 | Rela | affects localization | ISO | RELA (Homo sapiens) | 6480464 | CTD | Quercetin affects the localization of RELA protein | PMID:20386985 PMID:25830055 PMID:30171828 | Rela | decreases expression | ISO | RELA (Homo sapiens) | 6480464 | CTD | Quercetin results in decreased expression of RELA protein | PMID:23645742 PMID:27279714 | Rela | decreases expression | ISO | Rela (Mus musculus) | 6480464 | CTD | Quercetin results in decreased expression of RELA protein | PMID:29432836 | Rela | increases expression | ISO | RELA (Homo sapiens) | 6480464 | CTD | Quercetin results in increased expression of RELA mRNA | PMID:21632981 | Rela | multiple interactions | ISO | RELA (Homo sapiens) | 6480464 | CTD | [pterostilbene co-treated with Quercetin] affects the localization of RELA protein; [pterostilbene co-treated with Quercetin] results in decreased activity of [NFKB1 protein binds to RELA protein]; [Quercetin co-treated with dinitrophenyl-human serum albumin conjugate] results in decreased expression of RELA protein; AKT1 protein modified form inhibits the reaction [Quercetin affects the localization of RELA protein]; Quercetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] affects the localization of and results in increased activity of RELA protein]; Quercetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] affects the localization of RELA protein]; Quercetin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of RELA protein]; Quercetin inhibits the reaction [Glucose affects the localization of RELA protein]; Quercetin inhibits the reaction [IL1B protein results in increased expression of RELA protein]; Quercetin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of RELA protein]; Quercetin inhibits the reaction [nickel chloride affects the localization of RELA protein]; Quercetin inhibits the reaction [Palmitates results in increased phosphorylation of RELA protein]; Quercetin inhibits the reaction [RELA protein binds to PTGS2 promoter]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of and results in increased activity of RELA protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RELA protein]; Quercetin inhibits the reaction [TNF protein affects the localization of RELA protein]; Quercetin inhibits the reaction [TNF protein results in increased activity of RELA protein]; Quercetin promotes the reaction [prolinedithiocarbamate results in decreased expression of RELA protein]; Quercetin promotes the reaction [TLR4 protein affects the expression of RELA protein]; RELA protein affects the reaction [[pterostilbene co-treated with Quercetin] results in decreased expression of BCL2 protein] | PMID:15113938 PMID:16794257 PMID:17588137 PMID:18852136 PMID:18958421 PMID:19557821 PMID:20386985 PMID:20438634 PMID:21756928 PMID:21857970 PMID:22592909 PMID:22595400 PMID:23504962 PMID:27279714 PMID:30016632 PMID:31672514 | Rela | multiple interactions | ISO | Rela (Mus musculus) | 6480464 | CTD | [Quercetin co-treated with Oxygen] results in decreased expression of RELA protein; dorsomorphin inhibits the reaction [Quercetin inhibits the reaction [[TNF protein co-treated with INS1 protein] results in increased expression of RELA protein]]; Quercetin analog inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein]; Quercetin inhibits the reaction [[TNF protein co-treated with INS1 protein] results in increased expression of RELA protein]; Quercetin inhibits the reaction [Carbon Tetrachloride affects the localization of RELA protein]; Quercetin inhibits the reaction [HMGB1 protein results in increased activity of and affects the localization of RELA protein]; Quercetin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 affects the localization of RELA protein]; Quercetin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased activity of and affects the localization of RELA protein]; Quercetin inhibits the reaction [Lipopolysaccharides affects the localization of and results in increased activity of RELA protein]; Quercetin inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein]; Quercetin inhibits the reaction [Lipopolysaccharides results in increased activity of RELA protein]; Quercetin inhibits the reaction [Okadaic Acid results in increased phosphorylation of RELA protein]; Quercetin inhibits the reaction [RELA protein modified form binds to CXCL10 promoter]; Quercetin inhibits the reaction [RELA protein modified form binds to CXCL2 promoter]; Quercetin inhibits the reaction [TNF protein promotes the reaction [RELA protein binds to CXCL10 promoter]]; Quercetin inhibits the reaction [TNF protein promotes the reaction [RELA protein binds to CXCL2 promoter]]; TOLLIP protein affects the reaction [Quercetin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 affects the localization of RELA protein]] | PMID:16171798 PMID:17449583 PMID:18274639 PMID:19265175 PMID:20417174 PMID:20579867 PMID:21857970 PMID:23353651 PMID:23439570 PMID:23735482 PMID:27050422 PMID:27601294 PMID:29432836 | | ||||||||||||||||||||||
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