GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ccnd1 | decreases expression | EXP | | 6480464 | CTD | Quercetin results in decreased expression of CCND1 protein | PMID:9581680 | Ccnd1 | multiple interactions | EXP | | 6480464 | CTD | Quercetin inhibits the reaction [[Methylnitrosourea co-treated with Testosterone] results in increased expression of CCND1 protein]; Quercetin inhibits the reaction [[Warfarin co-treated with Vitamin K] results in increased expression of CCND1 mRNA]; Quercetin inhibits the reaction [Ethanol results in increased expression of CCND1 protein]; Quercetin inhibits the reaction [Oxygen deficiency results in decreased expression of CCND1 protein]; Quercetin inhibits the reaction [Warfarin results in increased expression of CCND1 mRNA] | PMID:18506933 PMID:23117658 PMID:25164625 PMID:26476374 | Ccnd1 | affects expression | ISO | CCND1 (Homo sapiens) | 6480464 | CTD | Quercetin affects the expression of CCND1 mRNA | PMID:32530119 | Ccnd1 | decreases expression | ISO | CCND1 (Homo sapiens) | 6480464 | CTD | Quercetin results in decreased expression of CCND1 mRNA; Quercetin results in decreased expression of CCND1 protein | PMID:12469199 PMID:12888923 PMID:15309432 PMID:18323654 PMID:18787224 PMID:19440933 PMID:20596804 PMID:20658310 PMID:25293876 PMID:30152185 | Ccnd1 | increases expression | ISO | CCND1 (Homo sapiens) | 6480464 | CTD | Quercetin results in increased expression of CCND1 mRNA | PMID:14715546 | Ccnd1 | multiple interactions | ISO | CCND1 (Homo sapiens) | 6480464 | CTD | [Cisplatin co-treated with Quercetin] results in increased expression of CCND1 mRNA; [Quercetin analog co-treated with Gold analog] results in decreased expression of CCND1 protein; [Quercetin co-treated with IL6 protein] results in decreased expression of CCND1 mRNA; [Quercetin co-treated with IL6 protein] results in decreased expression of CCND1 protein; Quercetin inhibits the reaction [IL6 protein promotes the reaction [STAT3 protein binds to CCND1 promoter]]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCND1 mRNA]; Quercetin inhibits the reaction [TNF protein results in increased expression of CCND1 protein]; Tamoxifen affects the reaction [Quercetin affects the expression of CCND1 mRNA] | PMID:12589822 PMID:20438634 PMID:22394507 PMID:27470402 PMID:27514524 PMID:32530119 | |
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